Semaglutide, a glucagon-like peptide receptor antagonist, significantly enhances glycemic control within the pancreas. By delaying gastric emptying and reducing glucagon secretion, semaglutide effectively curbs appetite, diminishes sugar cravings, and enhances the capacity to regulate eating habits. Numerous studies have demonstrated its remarkable efficacy, with patients achieving substantial weight loss averaging 30 pounds (16% of body weight) within a 12-week period.
Tirzepatide is also a a glucagon-like peptide receptor antogonist which basically improves glycemic control in the pancreas. This unique medication that mimics two hormones naturally found in the body: GLP-1 and GIP.
Tirzepatide also reduces the time for the stomach to empty its contents, suppressing appetite. Study’s have shown more significant weight loss with Tirzepatide and milder side effects as compared to Semaglutide. Using tirzepatide resulted in a weight loss of 17.8% (95% CI: 16.3%-19.3%) compared with 12.4% (95% CI: 11.5%-13.4%) for semaglutide.